Web Article Directory Curaçao: January 2009

Friday, 23 January 2009

Mtefel

Mtefel may be available in the countries listed below.

Ingredient matches for Mtefel

Piroxicam

Piroxicam is reported as an ingredient of Mtefel in the following countries:

Germany

International Drug Name Search

Actrapid NovoLet

Actrapid NovoLet may be available in the countries listed below.

Ingredient matches for Actrapid NovoLet

Insulin Injection, Soluble

Insulin Injection, Soluble human (a derivative of Insulin Injection, Soluble) is reported as an ingredient of Actrapid NovoLet in the following countries:

Germany

Hungary

Myanmar

International Drug Name Search

Thursday, 22 January 2009

Droxia

Generic Name: hydroxyurea (Oral route)

hye-drox-ee-ure-EE-a

Oral route(Capsule)

Treatment of patients with hydroxyurea may be complicated by severe, sometimes life-threatening, adverse effects. Hydroxyurea is mutagenic and clastogenic, and causes cellular transformation to a tumorigenic phenotype which implies a carcinogenic risk to humans. In patients receiving long-term hydroxyurea for myeloproliferative disorders, such as polycythemia vera and thrombocythemia, secondary leukemias have been reported. It is unknown whether this leukemogenic effect is secondary to hydroxyurea or is associated with the patients’ underlying disease .

Commonly used brand name(s)

In the U.S.

Droxia

Hydrea

Available Dosage Forms:

Capsule

Tablet

Therapeutic Class: Antineoplastic Agent

Pharmacologic Class: Antimetabolite

Uses For Droxia

Hydroxyurea is used to treat skin cancer (melanoma), a cancer of the white blood cells called chronic myelocytic leukemia (CML), and metastatic cancer (cancer that has spread) of the ovaries. This medicine may also be given together with radiation treatment for head and neck cancer (primary squamous cell cancer).

Hydroxyurea is also used in adult patients with sickle cell anemia to prevent painful episodes and reduce the need for blood transfusions. It works by making the red blood cells more flexible.

Hydroxyurea will interfere with the growth of cancer cells, which are eventually destroyed. Since the growth of normal body cells may also be affected, other unwanted effects will also occur. Some of these effects may be serious and must be reported to your doctor.

Before you begin treatment with hydroxyurea, you and your doctor should talk about the good this medicine will do as well as the risks of using it.

This medicine is available only with your doctor's prescription.

Before Using Droxia

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of hydroxyurea in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of hydroxyurea in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving hydroxyurea.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	D	Studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Rotavirus Vaccine, Live

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Adenovirus Vaccine Type 4, Live

Adenovirus Vaccine Type 7, Live

Bacillus of Calmette and Guerin Vaccine, Live

Didanosine

Influenza Virus Vaccine, Live

Measles Virus Vaccine, Live

Mumps Virus Vaccine, Live

Rotavirus Vaccine, Live

Rubella Virus Vaccine, Live

Smallpox Vaccine

Stavudine

Typhoid Vaccine

Varicella Virus Vaccine

Yellow Fever Vaccine

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper Use of hydroxyurea

This section provides information on the proper use of a number of products that contain hydroxyurea. It may not be specific to Droxia. Please read with care.

Take this medicine exactly as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.

This medicine comes with a patient information insert. Read and follow the instructions in the insert carefully. Ask your doctor if you have any questions.

Hydroxyurea should be handled with care and people who are not taking this medicine should be careful to avoid touching it. To decrease the chance of touching the medicine:

Wear disposable gloves when handling hydroxyurea or bottles containing hydroxyurea.

Wash your hands before and after contact with the bottle or capsules.

If powder from the capsule is spilled, you should wipe it up immediately with a damp disposable towel and discard it in a closed container, such as a plastic bag.

You should keep medicine away from children and pets.

You should contact your doctor for instructions on how to dispose of capsules that are past the expiration date.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (capsules):
- For cancer of the head and neck, ovaries, or skin:
  - Adults—Dose is based on body weight and must be determined by your doctor. The dose is 80 milligrams (mg) per kilogram (kg) of body weight, taken as a single dose every third day.
  - Children—Use and dose must be determined by your doctor.
- For chronic myelocytic leukemia (CML):
  - Adults—Dose is based on body weight and must be determined by your doctor. The dose is 30 milligrams (mg) per kilogram (kg) of body weight per day, taken as a single dose.
  - Children—Use and dose must be determined by your doctor.
- For sickle cell anemia:
  - Adults—Dose is based on body weight and must be determined by your doctor. The dose is 15 milligrams (mg) per kilogram (kg) of body weight per day, taken as a single dose. Your doctor may increase your dose as needed. However, the dose is usually not more than 35 mg per kg of body weight per day.
  - Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using Droxia

It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. Blood tests may be needed to check for unwanted effects.

Make sure your doctor knows if you are pregnant before you use this medicine. Using this medicine while you are pregnant can harm your unborn baby. If you think you have become pregnant while using the medicine, tell your doctor right away.

While you are being treated with hydroxyurea, and after you stop using it, do not have any immunizations (vaccines) without your doctor's approval. Hydroxyurea may lower your body's resistance and there is a chance you might get the infection the vaccine is meant to prevent. In addition, other persons living in your household should not get live vaccines (eg, nasal flu vaccine, measles, mumps, or rubella) since there is a chance they could pass the infection on to you. Also, avoid persons who have had a live vaccine. Do not get close to them and do not stay in the same room with them for very long. If you cannot take these precautions, you should consider wearing a protective face mask that covers the nose and mouth.

Hydroxyurea can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. It can also lower the number of platelets, which are necessary for proper blood clotting. If this occurs, there are certain precautions you can take, especially when your blood count is low, to reduce the risk of infection or bleeding:

If you can, avoid people with infections. Check with your doctor immediately if you think you are getting an infection or if you get a fever or chills, cough or hoarseness, lower back or side pain, or painful or difficult urination.

Check with your doctor immediately if you notice any unusual bleeding or bruising; black, tarry stools; blood in the urine or stools; or pinpoint red spots on your skin.

Be careful when using a regular toothbrush, dental floss, or toothpick. Your medical doctor, dentist, or nurse may recommend other ways to clean your teeth and gums. Check with your medical doctor before having any dental work done.

Do not touch your eyes or the inside of your nose unless you have just washed your hands and have not touched anything else in the meantime.

Be careful not to cut yourself when you are using sharp objects such as a safety razor or fingernail or toenail cutters.

Avoid contact sports or other situations where bruising or injury could occur.

Using this medicine for a long time may increase your risk of developing cancer of the blood (leukemia). Talk to your doctor if you have concerns about this risk.

This medicine may cause temporary loss of hair in some people. After treatment has ended, normal hair growth should return, although the new hair may be a slightly different color or texture.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Droxia Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Cough or hoarseness

fever or chills

lower back or side pain

painful or difficult urination

Less common

Black, tarry stools

blackening of the fingernails and toenails

blood in the urine or stools

pinpoint red spots on the skin

sores in the mouth and on the lips

unusual bleeding or bruising

Rare

Confusion

convulsions (seizures)

difficulty with urination

dizziness

headache

joint pain

seeing, hearing, or feeling things that are not there

swelling of the feet or lower legs

Incidence not known

Bleeding under the skin

blisters on the skin

bluish or pale color on the skin of the fingers or toes

coldness of the fingers or toes

crater-like lesions on the skin

itching skin

numbness or tingling of the fingers or toes

pain in the fingers or toes

unusual tiredness or weakness

weight loss

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Scaling of the skin on the hands and feet

severe darkening of skin color

soreness

sores in the mouth and on the lips

swelling of the palms and soles of the feet

violet flushing of the skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Diarrhea

drowsiness

loss of appetite

nausea or vomiting

Less common

Constipation

redness of skin at the place of irradiation

skin rash and itching

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Droxia side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Droxia resources

Droxia Side Effects (in more detail)
Droxia Use in Pregnancy & Breastfeeding
Drug Images
Droxia Drug Interactions
Droxia Support Group
0 Reviews for Droxia - Add your own review/rating

Droxia Prescribing Information (FDA)

Droxia MedFacts Consumer Leaflet (Wolters Kluwer)

Droxia Concise Consumer Information (Cerner Multum)

Hydroxyurea Monograph (AHFS DI)

Hydroxyurea Professional Patient Advice (Wolters Kluwer)

Hydroxyurea Prescribing Information (FDA)

Hydrea MedFacts Consumer Leaflet (Wolters Kluwer)

Hydrea Prescribing Information (FDA)

Compare Droxia with other medications

Anemia, Sickle Cell
Chronic Myelogenous Leukemia
Solid Tumors

Wednesday, 21 January 2009

RimabotulinumtoxinB

Pronunciation: RYE-ma-BOT-ue-li-num-TOX-in-B
Generic Name: RimabotulinumtoxinB
Brand Name: Myobloc

The effects of RimabotulinumtoxinB may spread from the injection site to other areas of the body, causing symptoms of a serious condition called botulism. These symptoms have been reported hours to weeks after patients have received RimabotulinumtoxinB. Symptoms may include loss of strength; muscle weakness; double or blurred vision; drooping eyelids; hoarseness; loss of voice; loss of bladder control; or trouble speaking, breathing, or swallowing. The risk may be greater in children being treated for spasticity (muscle spasms), but these symptoms may also occur in adults. Contact your doctor right away if these symptoms occur.

Severe and sometimes fatal breathing or swallowing problems have been reported. The risk may be greater in patients who already have breathing or swallowing problems. Tell your doctor if you have or are at risk of developing breathing or swallowing problems.

RimabotulinumtoxinB is used for:

Reducing the severity of abnormal head position and neck pain associated with a certain neck problem (cervical dystonia). It may also be used for other conditions as determined by your doctor.

RimabotulinumtoxinB is a neurotoxin. It works by blocking nerve impulses to the muscles, temporarily paralyzing the muscle.

Do NOT use RimabotulinumtoxinB if:

you are allergic to any ingredient in RimabotulinumtoxinB or another botulinum toxin product

you have an infection at the injection site

Contact your doctor or health care provider right away if any of these apply to you.

Before using RimabotulinumtoxinB:

Some medical conditions may interact with RimabotulinumtoxinB. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding

if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

if you have allergies to medicines, foods, or other substances

if you have nerve problems or diseases (eg, amyotrophic lateral sclerosis, motor neuropathy), muscle problems or diseases (eg, myasthenia gravis, Lambert-Eaton syndrome), bleeding disorders, seizures, or severe weakness or wasting of the muscles at the injection site

if you have a history of heart problems (eg, irregular heartbeat, a recent heart attack); swallowing problems; breathing problems (eg, asthma); eye problems (eg, glaucoma); or an overactive thyroid

if you have a skin infection, or inflammation, scarring, or other skin disorders at the injection site

if you plan to have surgery

if you have received RimabotulinumtoxinB or any other botulinum toxin product in the past, especially within the past 4 months

if you have never received RimabotulinumtoxinB or any other botulinum toxin product

if you have recently received an antibiotic by injection, or you also take muscle relaxants, allergy or cold medicine, or sleep medicine

Some MEDICINES MAY INTERACT with RimabotulinumtoxinB. Tell your health care provider if you are taking any other medicines, especially any of the following:

Aminoglycosides (eg, gentamicin), anticholinesterase medicines (eg, neostigmine), lincosamides (eg, clindamycin), magnesium, neuromuscular blockers (eg, atracurium), polymyxin, or quinidine because the risk of toxic effects may be increased

Anticoagulants (eg, warfarin) because the risk of bleeding at the injection site may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if RimabotulinumtoxinB may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use RimabotulinumtoxinB:

Use RimabotulinumtoxinB as directed by your doctor. Check the label on the medicine for exact dosing instructions.

RimabotulinumtoxinB comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get RimabotulinumtoxinB refilled.

RimabotulinumtoxinB is usually given as an injection at your doctor's office, hospital, or clinic.

If you miss a dose of RimabotulinumtoxinB, contact your doctor right away.

Ask your health care provider any questions you may have about how to use RimabotulinumtoxinB.

Important safety information:

RimabotulinumtoxinB may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use RimabotulinumtoxinB with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it. If loss of strength, muscle weakness, or vision problems occur, avoid driving or performing other possibly unsafe tasks.

Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.

Do not switch brands of RimabotulinumtoxinB. Contact your doctor if you have any questions.

RimabotulinumtoxinB contains albumin, which comes from human blood. There is a very rare risk of getting a viral disease or a central nervous system disease called Creutzfeldt-Jakob disease from products with albumin. No cases of these problems have been found in patients who have used RimabotulinumtoxinB.

To prevent injury, resume normal activities gradually after using RimabotulinumtoxinB.

RimabotulinumtoxinB should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.

PREGNANCY and BREAST-FEEDING: It is not known if RimabotulinumtoxinB can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using RimabotulinumtoxinB while you are pregnant. It is not known if RimabotulinumtoxinB is found in breast milk. If you are or will be breast-feeding while you use RimabotulinumtoxinB, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of RimabotulinumtoxinB:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Anxiety; back pain; dizziness; drowsiness; dry eyes; dry mouth; flu-like symptoms; headache; increased cough; indigestion; nausea; neck pain; pain, redness, swelling, or tenderness at the injection site; runny nose; sensitivity to light; sweating; upset stomach; weakness of the muscles at or near the injection site.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bleeding at the injection site; chest pain; difficulty swallowing or breathing; double or blurred vision, or other vision changes; drooping eyelid; fever, chills, or persistent sore throat; irregular heartbeat; loss of bladder control; loss of strength; paralysis; pneumonia; seizures; severe or persistent muscle weakness or dizziness; shortness or breath; speech changes or problems; swelling of the hands or feet; vaginal irritation, odor, or discharge; wheezing.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: RimabotulinumtoxinB side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include body weakness; difficulty breathing; paralysis.

Proper storage of RimabotulinumtoxinB:

RimabotulinumtoxinB is usually handled and stored by a health care provider. If you are using RimabotulinumtoxinB at home, store RimabotulinumtoxinB as directed by your pharmacist or health care provider. Keep RimabotulinumtoxinB out of the reach of children and away from pets.

General information:

If you have any questions about RimabotulinumtoxinB, please talk with your doctor, pharmacist, or other health care provider.

RimabotulinumtoxinB is to be used only by the patient for whom it is prescribed. Do not share it with other people.

If your symptoms do not improve or if they become worse, check with your doctor.

Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about RimabotulinumtoxinB. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

More RimabotulinumtoxinB resources

RimabotulinumtoxinB Side Effects (in more detail)
RimabotulinumtoxinB Use in Pregnancy & Breastfeeding
RimabotulinumtoxinB Drug Interactions
RimabotulinumtoxinB Support Group
0 Reviews for RimabotulinumtoxinB - Add your own review/rating

Myobloc Prescribing Information (FDA)

Myobloc Monograph (AHFS DI)

rimabotulinumtoxinB Concise Consumer Information (Cerner Multum)

rimabotulinumtoxinb Intramuscular Advanced Consumer (Micromedex) - Includes Dosage Information

Compare RimabotulinumtoxinB with other medications

Cervical Dystonia
Dystonia
Facial Wrinkles
Hyperhidrosis

Tuesday, 20 January 2009

Emycin

Emycin may be available in the countries listed below.

Ingredient matches for Emycin

Erythromycin

Erythromycin ethylsuccinate (a derivative of Erythromycin) is reported as an ingredient of Emycin in the following countries:

Vietnam

International Drug Name Search

Monday, 19 January 2009

Pravastatina Ratiopharm

Pravastatina Ratiopharm may be available in the countries listed below.

Ingredient matches for Pravastatina Ratiopharm

Pravastatin

Pravastatin sodium salt (a derivative of Pravastatin) is reported as an ingredient of Pravastatina Ratiopharm in the following countries:

Italy

Portugal

Spain

International Drug Name Search

Piperacetazine

In some countries, this medicine may only be approved for veterinary use.

Scheme

Rec.INN

CAS registry number (Chemical Abstracts Service)

0003819-00-9

Chemical Formula

C24-H30-N2-O2-S

Molecular Weight

410

Therapeutic Category

Neuroleptic

Chemical Name

Ethanone, 1-[10-[3-[4-(2-hydroxyethyl)-1-piperidinyl]propyl]-10H-phenothiazin-2-yl]-

Foreign Names

Piperacetazinum (Latin)
Piperacetazin (German)
Pipéracétazine (French)
Piperacetazina (Spanish)

Generic Names

Piperacetazine (OS: USAN)
PC-1421 (IS)
Piperacetazine (PH: USP XXII)

Brand Name

Kietud (veterinary use)
Virbac, France

International Drug Name Search

Glossary

IS	Inofficial Synonym
OS	Official Synonym
PH	Pharmacopoeia Name
Rec.INN	Recommended International Nonproprietary Name (World Health Organization)
USAN	United States Adopted Name

Click for further information on drug naming conventions and International Nonproprietary Names.

Tuesday, 13 January 2009

Ponuric

Ponuric may be available in the countries listed below.

Ingredient matches for Ponuric

Allopurinol

Allopurinol is reported as an ingredient of Ponuric in the following countries:

Indonesia

International Drug Name Search

Saturday, 10 January 2009

Ratica

Ratica may be available in the countries listed below.

Ingredient matches for Ratica

Ranitidine

Ranitidine is reported as an ingredient of Ratica in the following countries:

Thailand

International Drug Name Search

Monday, 5 January 2009

Doxazosin Germed

Doxazosin Germed may be available in the countries listed below.

Ingredient matches for Doxazosin Germed

Doxazosin

Doxazosin mesilate (a derivative of Doxazosin) is reported as an ingredient of Doxazosin Germed in the following countries:

Netherlands

International Drug Name Search

Sunday, 4 January 2009

Ocuflox

Generic Name: ofloxacin (Ophthalmic route)

oh-FLOX-a-sin

Commonly used brand name(s)

In the U.S.

Ocuflox

In Canada

Ofloxacin

Ophtho-Flox

Available Dosage Forms:

Solution

Therapeutic Class: Antibiotic

Chemical Class: Fluoroquinolone

Uses For Ocuflox

Ofloxacin is an antibiotic used to treat bacterial infections of the eye, such as conjunctivitis and corneal ulcers.

Ofloxacin is available only with your doctor's prescription.

Before Using Ocuflox

Allergies

Pediatric

Use is not recommended in infants up to 1 year of age. In children 1 year of age and older, this medicine is not expected to cause different side effects or problems than it does in adults.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of ophthalmic ofloxacin in the elderly with use in other age groups.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

Interactions with Medicines

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Cisapride

Dronedarone

Mesoridazine

Pimozide

Sparfloxacin

Thioridazine

Acarbose

Acecainide

Acetohexamide

Alfuzosin

Alosetron

Amiodarone

Amitriptyline

Amoxapine

Apomorphine

Arsenic Trioxide

Asenapine

Astemizole

Azimilide

Azithromycin

Benfluorex

Bretylium

Chloroquine

Chlorpromazine

Chlorpropamide

Ciprofloxacin

Citalopram

Clarithromycin

Clomipramine

Clozapine

Crizotinib

Dasatinib

Desipramine

Disopyramide

Dofetilide

Dolasetron

Droperidol

Erythromycin

Flecainide

Fluconazole

Gatifloxacin

Gemifloxacin

Gliclazide

Glimepiride

Glipizide

Gliquidone

Glyburide

Granisetron

Guar Gum

Halofantrine

Haloperidol

Ibutilide

Iloperidone

Imipramine

Insulin

Insulin Aspart, Recombinant

Insulin Glulisine

Insulin Lispro, Recombinant

Lapatinib

Levofloxacin

Lopinavir

Lumefantrine

Mefloquine

Metformin

Methadone

Miglitol

Moricizine

Moxifloxacin

Nilotinib

Norfloxacin

Nortriptyline

Octreotide

Ondansetron

Paliperidone

Pazopanib

Perflutren Lipid Microsphere

Posaconazole

Procainamide

Prochlorperazine

Promethazine

Protriptyline

Quetiapine

Quinidine

Quinine

Ranolazine

Salmeterol

Saquinavir

Sematilide

Sodium Phosphate

Sodium Phosphate, Dibasic

Sodium Phosphate, Monobasic

Solifenacin

Sorafenib

Sotalol

Sunitinib

Tedisamil

Telithromycin

Tetrabenazine

Tizanidine

Tolazamide

Tolbutamide

Toremifene

Trifluoperazine

Trimipramine

Troglitazone

Vandetanib

Vardenafil

Vemurafenib

Voriconazole

Ziprasidone

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Betamethasone

Corticotropin

Cortisone

Cosyntropin

Deflazacort

Dexamethasone

Didanosine

Fludrocortisone

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Warfarin

Interactions with Food/Tobacco/Alcohol

Proper Use of ofloxacin

This section provides information on the proper use of a number of products that contain ofloxacin. It may not be specific to Ocuflox. Please read with care.

To use:

First, wash your hands. Tilt the head back and with the index finger of one hand, press gently on the skin just beneath the lower eyelid and pull the lower eyelid away from the eye to make a space. Drop the medicine into this space. Let go of the eyelid and gently close the eyes. Do not blink. Keep the eyes closed for 1 to 2 minutes, to allow the medicine to come into contact with the infection.

If you think you did not get the drop of medicine into your eyes properly, use another drop.

To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). Also, keep the container tightly closed.

To help clear up your eye infection completely, keep using ophthalmic ofloxacin for the full time of treatment, even if your symptoms have disappeared. Do not miss any doses .

Dosing

For ophthalmic (eye drops) dosage form:
- For conjunctivitis:
  - Adults and children 1 year of age and older—Use 1 drop in the affected eye every two to four hours, while you are awake, for two days. Then, use 1 drop in each eye four times a day for up to five more days.
  - Infants up to 1 year of age—Use and dose must be determined by your doctor.
- For bacterial corneal ulcers:
  - Adults and children 1 year of age and older—Use 1 drop in the affected eye every thirty minutes while you are awake and 1 drop four to six hours after you go to bed, for two days. Then use 1 drop every hour while you are awake for up to seven more days. After the seventh, eighth, or ninth day, as instructed by your doctor, use 1 drop four times a day until your doctor determines that the treatment is complete.
  - Infants up to 1 year of age—Use and dose must be determined by your doctor.

Missed Dose

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Ocuflox

If your eye infection does not improve within 7 days, or if it becomes worse, check with your doctor.

Discontinue using these eye drops immediately and contact your physician at the first sign of a rash or an allergic reaction.

This medicine may cause your eyes to become more sensitive to light than they are normally. Wearing sunglasses and avoiding too much exposure to bright light may help lessen the discomfort.

Ocuflox Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare

Puffiness or swelling of eyes

signs of an allergic reaction, such as hives, itching, rash, swelling of face or lips, tightness in chest, troubled breathing, or wheezing

Check with your doctor as soon as possible if any of the following side effects occur:

Rare

Dizziness

More common

Burning of eye

Less common

Blurred vision

eye pain

feeling of something in the eye

increased sensitivity of eye to light

redness, irritation, or itching of eye, eyelid, or inner lining of eyelid

stinging, tearing, or dryness of eye

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Ocuflox side effects (in more detail)

More Ocuflox resources

Ocuflox Side Effects (in more detail)
Ocuflox Use in Pregnancy & Breastfeeding
Ocuflox Support Group
0 Reviews for Ocuflox - Add your own review/rating

Ocuflox Prescribing Information (FDA)

Ocuflox Concise Consumer Information (Cerner Multum)

Ocuflox Drops MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Ocuflox with other medications

Conjunctivitis, Bacterial
Corneal Ulcer
Ophthalmic Surgery

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